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Dear friends, September is coming to an end and so is this citizen science experiment. The time has come to reap the fruits of this enormous collective effort that we have all made together. During the last 3 months (July-September) the GENIGMA app remained open with new data from the breast cancer genome. The goal […]
Thanks to the collective effort of all the people who participated in the #GenigmaChallenge, in just 20 weeks 181 regions of the genome with chromosomal anomalies were identified in the T47D breast cancer cell line. We have named these regions Eureka! The games provided during the #GenigmaChallenge were prepared at 100k resolution, meaning that each […]
On 16 June heralded the conclusion of the #GenigmaChallenge, the first participative experiment to analyse the human genome through a mobile phone app, GENIGMA, in which more than 39,000 people from 154 countries participated. –> 600,287 solutions have been gathered in a matter of 20 weeks and 181 Eureka! regions, areas of the genome of […]
The game uses data from experiments conducted on breast cancer cells in the CRG lab. The experiments produced interaction maps between all the genomic regions of the breast cancer cells analysed. Each element of an interaction map is an experimental measure of the number of interactions that two chromosomal regions make within the nucleus. Yasmina […]
What do I have to do?Rearrange the game pieces and try to get a score as high as possible. What do the symbols inside each piece mean?Nothing, it just helps you to identify any piece form the others. What do the colours of the pieces mean?The colour of the pieces goes from red to green. […]
What is GENIGMA? Genigma is both a game and a citizen science project. The game enlists players to solve puzzles and help find the correct order of gene sequences in cancer. Cancers have a huge number of mutations and chromosomal abnormalities that make it difficult to study. Players help us deduce the correct order of the […]
Reference genomes have great benefits for medicine: they allow the discovery of the molecular mechanisms responsible for many diseases and facilitate the diagnosis and development of more specific therapies. Knowing the genomic map of cancer cells can provide us with useful information to understand how they work. In some types of cancer, we do not […]